
颜凯程,前沿交叉研究院,副教授。
邮箱:kai-chengyan@njau.edu.cn 办公地点:10号楼A325,卫岗逸夫楼1000-7
研究领域与方向: 荧光探针与生物传感,人或兽疾病标志物传感检测,疾病诊疗体系构建
教育经历 :
2020/09—2024/06 英国巴斯大学,化学系, 博士
2017/09—2020/06 华东理工大学,化学与分子工程学院 硕士
2013/09—2017/06 上海海洋大学,工程学院, 本科
工作经历 :
2025/03—至今 南京农业大学,前沿交叉研究院, 副教授
近五年代表性论文(第一作者):
1. K.-C. Yan, F.-F. Guo, L. Zhang, N. Thet, A. C. Sedgwick, Y. Wang*, Z.-H. Xu*, T. D. James*, A. T. A. Jenkins*. Turn-on and ratiometric detection of carboxylesterases using acetyl-based fluorescent strategies for bacterial applications. Sensors and Actuators B: Chemical, 2024, 404, 135121.
2. A. C. Sedgwick1, K.-C. Yan1, D. N. Mangel, Y. Shang, A. Steinbrueck, H.-H. Han, J. T. Brewster II, X.-L. Hu, D. W. Snelson, V. M. Lynch, H. Tian, X.-P. He*, J. L. Sessler*. Deferasirox (ExJade): An FDA-Approved AIEgen Platform with Unique Photophysical Properties. Journal of the American Chemical Society, 2021, 143, 3, 1278.
3. Y.-F. Song1, K.-C. Yan1, P. Liu, W.-N. Wu*, X.-L. Zhao, N. Thet, Y. Wang*, Y.-C Fan, Z.-H. Xu*, T. D. James*, A. T. A. Jenkins*. Ferrocene-chalcone-based probe for the fluorescent and electrochemical dual-mode detection of carboxylesterase. Sensors and Actuators B: Chemical, 2024, 405, 135284.
4. C. Zhang1, D.-T. Shi1, K.-C. Yan1, A. C. Sedgwick, G.-R. Chen, X.-P. He, T. D. James, B. Ye*, X.-L. Hu*, D. Chen*. A glycoconjugate-based gold nanoparticle approach for the targeted treatment of Pseudomonas aeruginosa biofilms. Nanoscale, 2020, 12, 23234.
5. K.-C. Yan, N. Thet, R. A. Heylen, A. C. Sedgwick*, T. D. James*, A. T. A. Jenkins*, X.-P. He*. Repurposing a long-wavelength fluorescent boronate probe for the detection of reactive oxygen species (ROS) in bacteria. Sensors & Diagnostics, 2023, 2, 1181.
6. K.-C. Yan, J. E. Gardiner, A. C. Sedgwick, N. Thet, R. A. Heylen, T. D. James*, A. T. A. Jenkins*, X.-P. He*. A TCF-based fluorescent probe to determine nitroreductase (NTR) activity for a broad-spectrum of bacterial species. Chemical Communications, 2023, 59, 8278.
7. K.-C. Yan, B. L. Patenall, J. E. Gardiner, R. A. Heylen, N. Thet, X.-P. He, A. C. Sedgwick*, T. D. James*, A. T. A. Jenkins*. TCF-based fluorescent probe for monitoring superoxide anion produced in bacteria under chloramphenicol- and heat-induced stress. Chemical Communications, 2022, 58, 13103.
8. K.-C. Yan, Q. Cao, N. Thet, A. C. Sedgwick, T. D. James*, A. T. A. Jenkins*. A simple coumarin-based system for the effective detection of superoxide in bacteria. Results in Chemistry, 2024, 7, 101244.
9. A. C. Sedgwick1, K.-C. Yan1, D. N. Mangel, Y. Shang, A. Steinbrueck, H.-H. Han, J. T. Brewster II, X.-L. Hu, D. W. Snelson, V. M. Lynch, H. Tian, X.-P. He, J. L. Sessler. Deferasirox (ExJade): A Fluorescent Pro-Chelator Active Against Antibiotic Resistant Bacteria. ChemRxiv, 2020, https://doi.org/10.26434/chemrxiv.12040518.
10. B. Thomas1, K.-C. Yan1, X.-L. Hu, M. Donnier-Marechal, G.-R. Chen*, X.-P. He*, S. Vidal*. Fluorescent glycoconjugates and their applications. Chemical Society Reviews, 2020, 49, 593.
11. K.-C. Yan, A. Steinbrueck, A. C. Sedgwick*, T. D. James*. Fluorescent Chemosensors for Ion and Molecule Recognition: The Next Chapter. Frontiers in Sensors, 2021, 2, 731928.
12. X.-L. Hu1, Y. Shang1, K.-C. Yan1, A. C. Sedgwick, H.-Q. Gan, G.-R. Chen, X.-P. He*, T. D. James*, D. Chen*. Low-dimensional nanomaterials for antibacterial applications. Journal of Materials Chemistry B, 2021, 9, 3640.
13. S. Xu1, K.-C. Yan1 , Z.-H Xu*, Y. Wang*, T. D. James*. Fluorescent probes for targeting the Golgi apparatus: design strategies and applications. Chemical Society Reviews, 2024, 53, 7590.
学术兼职经历:
《Frontiers in Biomaterials Science》 主题编辑