高宗玉，前沿交叉研究院，讲师
教育经历 ：
2015/09—2021/06 中国农业大学，微生物学专业， 博士
2011/09—2015/06 南京农业大学，生物科学专业， 本科
工作经历 :
2022/06—2025/06 英国牛津大学，Department of Biology，博士后研究助理
2025/08—至今 南京农业大学，前沿交叉研究院， 讲师
研究领域与方向：
主要聚焦于植物与丛枝菌根真菌 (Arbuscular Mycorrhizal Fungi, AMF) 共生的分子调控机制。丛枝菌根是真菌与植物根系之间形成的互惠共生体系，在促进植物吸收磷等关键矿质元素、提升抗逆能力及生态适应性方面发挥着重要作用。尽管AM共生在农业可持续发展中具有巨大潜力，但植物如何在分子层面识别并调控这种共生关系，仍有许多未解之谜。
本实验室特别关注植物源信号分子——独脚金内酯 (strigolactone) 与烟酰内酯(karrikin) 在AM共生建立与维持过程中的作用机制。独脚金内酯作为植物分泌信号，能促进AM真菌孢子萌发和菌丝分枝，从而增强共生建立；而烟酰内酯信号通路虽最初与火灾后植物萌发相关，但其与独脚金内酯途径共享部分受体与信号组分，暗示两者在调控植物-真菌互作中可能存在复杂的交互关系。
我们致力于通过分子遗传学、细胞生物学及组学技术，解析这两条信号通路如何影响植物对AM真菌的识别、信号转导及丛枝形成过程，从而阐明植物在共生关系中对真菌伙伴的动态调控机制。
欢迎感兴趣的同学加入我们的研究团队。
联系方式
邮箱：2025059@njau.edu.cn
办公地点：滨江校区食品楼A413
发表文章
Zongyu Gao, Dingliang Zhang, Xiaoling Wang, Xin Zhang, Zhiyan Wen, Qianshen Zhang, Dawei Li, Savithramma P. Dinesh-Kumar, Yongliang Zhang*, 2022, Coat proteins of necroviruses target 14-3-3a to subvert MAPKKKα-mediated antiviral immunity in plants, Nature Communications, 13(1): 716. (Editors’Highlight; Web of Science高被引论文).
Zongyu Gao, Heng Pu, Jingyuan Liu, Xiaoling Wang, Chenchen Zhong, Ning Yue, Ziding Zhang, Xian-bing Wang, Chenggui Han, Jialin Yu, Dawei Li, Yongliang Zhang*, 2021, Single amino acid in the coat protein determines host-specific systemic infectivity of Tobacco necrosis virus-AC in Nicotiana benthamiana and soybean, Molecular Plant-Microbe Interactions, 34(1): 49-61. (亮点文章)
Dingliang Zhang, Zongyu Gao, He Zhang, Yizhou Yang, Xinxin Yang, Xiaofei Zhao, Hailong Guo, Ugrappa Nagalakshmi, Dawei Li, Savithramma P. Dinesh-Kumar*, Yongliang Zhang*, 2023, The MAPK-ALFIN-LIKE 7 module negatively regulates ROS scavenging genes to promote NLR-mediated immunity, Proceedings of the National Academy of Sciences USA, 20(3): e2214750120. (Trends in Plant Science杂志Spotlight专文评述; Web of Science高被引论文).
Serena A. Qiao, Zongyu Gao, Ronelle Roth*, 2023, A perspective on cross-kingdom RNA interference in mutualistic symbioses. New Phytologist, 240: 68-79.
Chenchen Zhong#, Wenli Li#, Xinyu Zhang, Dingliang Zhang, Zhiyan Wen, Wen Song, Zhihao Jiang, Zongyu Gao, Hailong Guo, Guozhi Bi, Zhiyong Liu, Dawei Li, Savithramma P. Dinesh-Kumar, Yongliang Zhang*, 2025, A cell wall-associated kinase phosphorylates NLR immune receptor to negatively regulate resistosome formation. Nature Plants, 11, 561–579 (2025). https://doi.org/10.1038/s41477-025-01949-3
Qianshen Zhang#, Zhiyan Wen#, Xin Zhang#, Jiajie She, Xiaoling Wang, Zongyu Gao, Ruiqi Wang, Xiaofei Zhao, Zhen Su, Zhen Li, Dawei Li, Xiaofeng Wang, Yongliang Zhang*, 2023, RETICULON-LIKE PROTEIN B2 is a pro-viral factor co-opted for the biogenesis of viral replication organelles in plants, Plant Cell, 35(8), 3127-3151.
Ning Yue, Zhihao Jiang, Xuan Zhang, Zhenggang Li, Xueting Wang, Zhiyan Wen, Zongyu Gao, Qinglin Pi, Yongliang Zhang, Xian-Bing Wang, Chenggui Han, Jialin Yu, Dawei Li*, 2022, Palmitoylation of γb protein directs a dynamic switch between Barley stripe mosaic virus replication and movement, EMBO Journal, 41(13): e110060.
Ning Yue#, Zhihao Jiang#, Qinglin Pi, Meng Yang, Zongyu Gao, Xueting Wang, He Zhang, Fengtong Wu, Xuejiao Jin, Menglin Li, Ying Wang, Yongliang Zhang, Dawei Li*, 2024, Zn2+-dependent association of cysteine-rich protein with virion orchestrates morphogenesis of rod-shaped viruses, PLoS Pathogens, 20(6): e1012311.
Xiaoling Wang#, Xiuling Cao#, Min Liu, Ruiqi Zhang, Xin Zhang, Zongyu Gao, Xiaofei Zhao, Kai Xu, Dawei Li, Yongliang Zhang*, 2018, Hsc70-2 is required for Beet black scorch virus infection through interaction with replication and capsid proteins, Scientific Reports, 8: 4526.
